Thank you for the detailed information. We need additional information to assist you, please answer the following question.
Is your computer on a domain?
We have to diagnose the issue. let’s try by uninstalling, reinstalling the Microsoft Mouse and Keyboard Center application.
Refer to these steps to uninstall a program.
a. press Windows +X on your keyboard.
b. Click on Control Panel.
c. From Control Panel window choose large icon view and open Programs and Features.
d. Right click on the Program and click on uninstall
Download Mouse and Keyboard Center to get the most out of Windows 8.
Please do let us know if you need further help.